Stable gastric pentadecapeptide BPC-157 in therapy of gastrointestinal and liver disorders
In rodent Achilles tendon transection models: BPC-157 administration led to: Higher tensile strength Faster load-bearing capacity Improved structural continuity These are functional endpoints meaning the tissue wasnt just healing histologically, but mechanically
It exerts its effects primarily within the tissue microenvironment at or near the site of injury
Kjersti Grtta Vetvik: No disclosures related with the specific topic, but has received honoraria for lecturing and/or participation in advisory boards from Novartis, TEVA, Roche, Pfizer, Lundbeck, Eli Lilly
In animal studies, very high doses of sermorelin (several times the human dose) produced minor variations in fetal development in rats and rabbits
Cartilage studies take longer because cartilage lacks blood vessels and renews slowly